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Integrated multimodal (tES, EEG, fNIRS) neurotechnology
Silverline provides integrated multimodal (tES, EEG, fNIRS) neurotechnology systems designed for synchronized acquisition and advanced experimental control.
Standard Hardware Configurations:
tES + EEG (Starstim)
EEG + fNIRS (Enobio + Brite)
tES + EEG + fNIRS (Starstim + Brite)
Integration Software Platforms:
Real-time Metrics and Closed-loop stimulation paradigms (OptEStim)
Synchronized multimodal recordings (MyndSens Pro)
Hardware Systems are supplied in partnership with Neuroelectrics and Artinis Medical Systems and delivered directly to laboratories internationally.
Silverline provides the integration software platforms and training to get a project up and running efficiently from equipement installation to experimental setup/design and analysis/publication of results.
The integration training is included when purchasing a Starstim fNIRS system from Silverline
training service packages
training service packages
Whether you are interested in developing advanced level closed-loop tES projects or just want to setup integrated tES, fNIRS and/or EEG experiments, Silverline offers 2 levels of training support packages to help you through the difficult research and development decision making processes:
Standard Training Package
Research training support provided by Silverline Research will include:
training to help setup the tES, fNIRS, EEG cap integration and software synchronization for any compatible tES, EEG, and fNIRS system.
Specific advice/training on fNIRS, EEG and tES experimental setup, design and analysis methods based on user needs.
The 20hrs of research support is for 1 year and includes face-to-face online meetings of 1-2hr duration each plus any additional time allocated to perform research and interpretation services.
Premium Training Package
The Premium Package allows for 40 hours of dedicated support for the duration of the project.
additional standard packages (20hrs) can be added for more demanding projects.
Proprietary Software Platforms
OptEStim
A real-time experimentation and closed-loop stimulation workflow platform designed to simplify multimodal research and reduce scripting complexity.
OptEStim provides:
Synchronous tracking of brain activity (EEG) and hemodynamics (fNIRS)
instant visualizations of EEG-fNIRS analytics
Open-loop, Entrainment and Conditional closed-loop programs
Results of session as raw and detailed EEG and fNIRS analytics of all channels are provided in csv format
MyndSens Pro
A multimodal (fNIRS, EEG, any sensor) data streaming and synchronisation suite integrating Lab Streaming Layer (LSL) compatible systems into a unified, synchronised acquisition format (XDF).
Together, these systems enable high-fidelity neurotechnology experimentation and deployment.
OptEStim: Our Real-Time Closed-Loop Platform
Simplifies advanced multimodal tES-EEG/fNIRS experiment setups
Real-time EEG-fNIRS monitoring and analytics
OptEStim platform offers advanced software-level capabilities for brain-state determination on an easy-to-use graphical user interface that allows real-time monitoring and analysis of EEG and fNIRS metrics using the streaming feature (e.g. EEG-Alpha peak, COG and fNIRS-O2Hbmean), including heart rate (HR) and variability (HRV) from fNIRS signals.
Closed-Loop control of tES with EEG-fNIRS
OptEStim platform provides different open-loop (i.e., standard tES protocols) and closed-loop (Entrainment and Conditional programs included) programs to run experiments using the Starstim tES parameters (tDCS, tACS, tRNS and hybrid tDCS/tACS/tRNS) using EEG and/or fNIRS metrics as user-defined thresholds to close the loop. The Entrainment closed-loop program allows the user to define the EEG metric (e.g., initial Alpha peak power) to close the loop; while the Conditional closed-loop program allows both EEG (e.g., Alpha COG, Gamma peak power) and fNIRS (Mean O2Hb, HHb, HR, HRV) metrics to set the threshold for tES.
Quickly learn advanced level tES-fNIRS/EEG experimental designs
This OptEStim platform offers the simplest and quickest way to get started on leading advanced brain state monitoring and closed-loop experiments without the demanding software development and training times. Therefore enabling faster tES protocol development and pilot testing of protocols for further research and clinical projects. Bespoke closed-loop programs can be developed for your specific research needs.
OptEStim software (Beta) provides:
Synchronous tracking of brain activity (EEG) and hemodynamics (fNIRS)
instant visualizations of EEG-fNIRS analytics
Open-loop, Entrainment and Conditional closed-loop programs
Results of session as raw and detailed EEG and fNIRS analytics of all channels are provided in csv format
OptEStim is currently in Beta mode, which is provided as a service of the Silverline Training packages. OptEStim is currently configured with the Starstim fNIRS system. Requests for demonstration of the OptEStim software with the Starstim fNIRS system are provided on request
fNIRS functionality
fNIRS functionality
Number of channels: 8 or 27 channels
Sampling rate: up to 150 Hz
Light source: LED (2x wavelengths per transmitter)
Wavelengths: 760, 850 nm
Optode distance: 30 mm
EEG functionality
EEG functionality
Number of channels: 8, 20, or 32 channels
Sampling rate: 500 Hz
Bandwidth: 0 to 125 Hz (DC coupled)
Resolution: 24 bits – 0,05 µV resolution
Noise: < 1 µV RMS
CMRR: -115 dB
Input impedance: 1 GΩ
tES functionality
tES functionality
Number of channels: 8, 20, or 32 channels
Sampling rate: 1000 Hz
Frequency range: 0 to 250 Hz (tACS) and 0 to 500 Hz (tRNS)
Stimulation types: tDCS, tACS and tRNS
Maximum current per channel: ± 2mA
Current accuracy: 1%
Current resolution: 1 μA
Voltage: ± 15 V per electrode (30 V potential difference)
Silverline Research also offers a collaboration option to integrate OptEStim into a prospective closed-loop research project
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